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Christian McCaffrey
Close to yardage milestone
RBSan Francisco 49ers
December 13, 2025
McCaffrey needs just 145 more yards from scrimmage to reach the 1,800-yard mark for the fifth time in his NFL career, per NFL.com.
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Jahmyr Gibbs
Close to surpassing TD record
RBDetroit Lions
December 13, 2025
Gibbs has 47 receiving or rushing touchdowns since entering the league in 2023, and with one more score, he would surpass Hall of Fame running back Barry Sanders for the most touchdowns by a player both in their first three career seasons and before their 24th birthday, per NFL.com.
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Emanuel Wilson
Could get more Week 15 carries
RBGreen Bay Packers
December 11, 2025
Wilson could see an expanded workload Sunday against the Broncos, as Matt Schneidman of The Athletic reports that Josh Jacobs didn't practice Thursday and is day-to-day due to a knee injury.
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Bam Knight
Likely lead back for rest of 2025
RBArizona Cardinals
December 11, 2025
Knight is poised to operate as the top option in Arizona's backfield on early downs for the remainder of the 2025 season, as Darren Urban of the Cardinals' official site reports that Trey Benson will spend the remainder of the 2025 season on injured reserve due to a knee injury.
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Trey Benson
Done for 2025 campaign
RBArizona Cardinals
December 11, 2025
Head coach Jonathan Gannon revealed Wednesday that Benson will spend the remainder of the 2025 season on injured reserve due to a knee injury, per Darren Urban of the Cardinals' official site.
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Dare Ogunbowale
Could have bigger role in Week 15
RBHouston Texans
December 11, 2025
Ogunbowale could be in line for a larger role in Week 15 against the Cardinals, as Woody Marks and Nick Chubb were both sidelined at Wednesday's practice.
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Keaton Mitchell
Drew interest at trade deadline
RBBaltimore Ravens
December 8, 2025
Mitchell was the subject of trade inquiries from multiple teams at the trade deadline, but the Ravens rebuffed the offers, Mike Garafolo of NFL Network reports.
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De'Von Achane
May not miss time
RBMiami Dolphins
December 8, 2025
Achane doesn't believe he'll miss any time as a result of the rib injury he suffered in Sunday's win over the Jets, Cameron Wolfe of NFL Network reports.
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Jaylen Wright
Could have expanded role in Week 15
RBMiami Dolphins
December 7, 2025
Wright could take on a larger workload in Week 15 against the Steelers, as De'Von Achane exited the Week 14 win over the Jets due to a rib injury.
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Tony Pollard
Facing tough Browns run defense
RBTennessee Titans
December 6, 2025
Pollard is in for a tough battle Sunday against a Browns run defense that allows a league-best 31 percent success rate on opposing runs, Seth Walder of ESPN reports.
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Bam Knight
Possible elevated receiving role
RBArizona Cardinals
December 5, 2025
Knight could be in for extra pass-catching work out of the backfield in Sunday's game against the Rams due to the Cardinals being down two wide receivers, per Josh Weinfuss of ESPN.com.
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Breece Hall
Chance for first 1,000-yard season
RBNew York Jets
December 4, 2025
Hall needs 166 rushing yards over the Jets' final five games of the 2025 regular season to become the team's first 1,000-yard rusher since Chris Ivory in 2015, per Rich Cimini of ESPN.com.
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Kyren Williams
Likely to play through ankle issue
RBLos Angeles Rams
December 4, 2025
Head coach Sean McVay said Wednesday that he expects Williams to play Sunday against the Cardinals, per Adam Grosbard of The Orange County Register.
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Kimani Vidal
Likely to be joined by Hampton soon
RBLos Angeles Chargers
December 4, 2025
Head coach Jim Harbaugh said Wednesday that Omarion Hampton is "on track and looking good" for a Week 14 return against the Eagles, per Eric Smith of the Chargers' official site, so Vidal's time as the lead back is likely coming to a close.
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Omarion Hampton
On track for Week 14
RBLos Angeles Chargers
December 4, 2025
Head coach Jim Harbaugh said Wednesday that Hampton is "on track and looking good" for a Week 14 return against the Eagles, though Harbaugh said the team still wants to see how the week of practice unfolds regarding Hampton's ankle injury, Eric Smith of the Chargers' official site reports.
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Devin Neal
In line for second straight start
RBNew Orleans Saints
December 4, 2025
Neal is likely to make a second consecutive start in Week 14 against the Buccaneers, as Alvin Kamara didn't practice Thursday due to knee and ankle injuries.
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RJ Harvey
Improving in pass protection
RBDenver Broncos
December 2, 2025
Harvey has improved as a pass blocker and could see increased playing time down the stretch, Jeff Legwold of ESPN reports.
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Jahmyr Gibbs
Extension candidate in offseason
RBDetroit Lions
December 1, 2025
Gibbs is expected to get a contract extension offer from the Lions once he's eligible this offseason, Ian Rapoport of NFL Network reports.
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Jordan Mason
Could be back in lead role Week 14
RBMinnesota Vikings
November 30, 2025
Mason could be in line to lead Minnesota's backfield in Week 14 against the Commanders, as Ben Goessling of The Minnesota Star Tribune reports that Aaron Jones injured his shoulder during Sunday's 26-0 loss to the Seahawks.
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Michael Carter
Could be Cardinals' RB1 for Week 13
RBArizona Cardinals
November 29, 2025
Carter would be poised to lead the Cardinals' backfield against the Buccaneers on Sunday if Bam Knight is unable to play due to a knee injury.
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James Cook
Facing depleted Steelers front
RBBuffalo Bills
November 29, 2025
Cook has played a big role in the Bills' league-best rushing attack this season, and he faces a Steelers defense Sunday that will be without rookie defensive lineman Derrick Harmon due to a knee injury, Brooke Pryor of ESPN reports.
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Ashton Jeanty
More carries under new OC?
RBLas Vegas Raiders
November 29, 2025
Ryan McFadden of ESPN believes interim offensive coordinator Greg Olson will deploy more rushing plays for Jeanty for the rest of the regular season, starting with Sunday's AFC West tilt against the Chargers.
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Kimani Vidal
Retaining top role Sunday
RBLos Angeles Chargers
November 28, 2025
Vidal is slated to serve as the Chargers' No. 1 running back in Sunday's game against the Raiders due to Omarion Hampton remaining on injured reserve, Kris Rhim of ESPN.com reports.
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Omarion Hampton
Remaining out in Week 13
RBLos Angeles Chargers
November 28, 2025
Hampton, who's in the final stages of his recovery from an ankle fracture, has been ruled out for Sunday's Week 13 matchup against the Raiders, Kris Rhim of ESPN.com reports.
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Keaton Mitchell
Larger role expected Thursday
RBBaltimore Ravens
November 27, 2025
Mitchell's likely to see a bump in touches Thursday against the Bengals, as Justice Hill has been ruled out due to a neck injury.
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