Friday's NBA DFS slate on DraftKings features seven games packed with opportunity. Jamal Murray headlines the elite tier after a season-high 53-point performance, while Donovan Mitchell looks to stay hot against a vulnerable Heat defense. In the mid-range, Reed Sheppard continues to deliver across the stat sheet as Houston's starter, and Derrick Jones offers well-rounded value against Indiana's porous defense. Several value plays also stand out, including Taylor Hendricks and Isaiah Jackson, both poised for productive nights. Here's a full breakdown of the top DraftKings NBA picks across every price range, plus key injuries and matchups to monitor.
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DraftKings Main Slate NBA Games Today
LAC at IND: Clippers on three-game win streak; Pacers 1-9 in last 10 games
ATL at BOS: Hawks 9-1 in last 10 games; Celtics 7-3 in last 10 games
MIA at CLE: Heat 16-20 on road; Cavs 23-14 at home
CHI at OKC: Bulls 11-23 on road; Thunder 9-1 in last 10 games
HOU at MEM: Rockets on two-game slide; Grizzlies 12-22 at home, 1-9 in last 10 games
NOP at TOR: Pelicans on three-game slide; Raptors 19-16 at home
UTA at DEN: Jazz on three-game slide; Nuggets on four-game win streak
For the latest spreads and over/unders, visit RotoWire's NBA Odds page. There you can also find player props, futures, picks, articles and sportsbook bonus codes.
NBA Injuries Today
For all the latest updates, visit RotoWire's NBA Injury News page and our comprehensive NBA Injury Report.
IND - Obi Toppin (back): Questionable
ATL - Jock Landale (shoulder): Questionable
BOS - Jaylen Brown (calf), Nikola Vucevic (finger): OUT
CLE - Dean Wade (ankle), Jaylon Tyson (toe): OUT
CHI - Nick Richards (elbow), Guerschon Yabusele (ankle): Questionable; Anfernee Simons (wrist): OUT
OKC - Chet Holmgren (hip): OUT
MEM - Ty Jerome (ankle), Jaylen Wells (toe): OUT
NOP - Dejounte Murray (Achilles), Trey Murphy (ankle): OUT
TOR - Immanuel Quickley (foot): OUT
UTA - Isaiah Collier (hamstring), Keyonte George (hamstring), Lauri Markkanen (hip): OUT
Elite NBA DFS Players
Guards
Jamal Murray, Nuggets 
($9,100) vs. Jazz
Murray is coming off a season-high 53-point performance and is averaging 25.3 points, 4.6 rebounds and 6.2 assists over the last 10 games. He has a great chance to continue to fill the boxscore against the Jazz, who are shorthanded in the backcourt and give up the league's most points and most three-pointers per game.
Donovan Mitchell, Cavaliers 
($9,300) vs. Heat
Mitchell is averaging 26.4 points, 4.6 rebounds, 5.3 assists and 1.1 steals over nine appearances since returning from a four-game absence. He is likely to keep rolling in the second of back-to-back meetings with the Heat, after he finished with 42.0 DK points in their previous encounter. The Heat also give up the league's 10th-most three-pointers per game.
Forwards/Centers
Kevin Durant, Rockets 
($9,000) at Grizzlies
Durant is averaging 25.3 points, 5.0 rebounds, 4.4 assists, 0.9 steals and 0.8 blocks over the last 10 games, including three with over 50 DK points. He has a great chance to prosper against a depleted Grizzlies lineup, especially as they give up the league's fifth-most points per game to opposing small forwards.
Scottie Barnes, Raptors 
($8,900) vs. Pelicans
Barnes topped 40 DK points in four of the last six games and is averaging 15.7 points, 6.6 rebounds, 6.2 assists, 1.5 steals and 1.1 blocks over 10 outings. He should keep up the strong play against the Pelicans, who are giving up the league's seventh-most points in the paint and sixth-most rebounds per game.
Alperen Sengun ($8,900) at Grizzlies
Sengun is averaging 24.8 points, 8.8 rebounds, 7.2 assists, 1.0 steals and 1.2 blocks over five games since returning from a two-game absence. He should continue to stuff the stat sheet with a favorable matchup against the Grizzlies, who give up the league's eighth-most points in the paint and the fourth-most rebounds per game to opposing centers.
Expected NBA DFS Chalk
Jalen Johnson, Hawks 
($10,600) at Celtics
Johnson turned in 55.0 DK points in the last game, which marked his return from a two-game absence. He is also averaging 21.6 points, 8.8 rebounds, 9.0 assists and 1.2 steals over his last 10 appearances and finished with 48.5 DK points in his previous encounter with the Celtics. He is likely to keep up the strong play while his team is rolling and is set to take on a shorthanded Celtics club.
Mid-Range NBA DFS Money
Reed Sheppard, Rockets ($6,100) at Grizzlies
Sheppard is up for a fifth straight start after averaging 15.0 points, 4.8 rebounds, 6.8 assists, 2.3 steals and 1.0 blocks over the last four games, including racking up a high of 58.5 DK points in that span. He has a good opportunity to keep up the production against the Grizzlies, who are shorthanded in the backcourt and give up the league's fourth-most threes per game.
Derrick Jones, Clippers 
($5,500) at Pacers
Jones is averaging 10.0 points, 4.7 rebounds, 2.0 assists, 1.4 steals and 1.0 blocks over the last 10 games, including four outings with more than 30 DK points. He has a great chance to pad his stats against the Pacers' lackluster defense, as they give up the league's fifth-most points and third-most rebounds per game.
NBA DFS Value Picks
Bruce Brown, Nuggets ($3,700) vs. Jazz
Brown is averaging 8.2 points, 3.0 rebounds and 1.6 assists over the last 10 games, including four with over 20 DK points. He is likely to do well against a shorthanded Jazz squad that also gives up the league's fourth-highest field-goal percentage and fifth-most turnovers per game.
Taylor Hendricks, Grizzlies 
($4,500) vs. Rockets
Hendricks is averaging 11.6 points, 4.8 rebounds, 1.2 assists, 1.8 steals and 1.5 blocks over his last 10 appearances, including four games with at least 30 DK points and a high of 41.0. He is in line for a second consecutive start and should see plenty of playing time to help pad his stats despite facing a tougher opponent.
Isaiah Jackson, Clippers ($4,300) at Pacers
Jackson is finding his groove, averaging 10.2 points, 5.6 rebounds, 1.6 assists and 1.2 blocks in 18.6 minutes per game over the last five games. He is up for an ideal chance to thrive against the Pacers, who give up the league's second-most points in the paint.
