Coors Field causes problems for many pitchers, but not Matt Cain, who has historically fared very well against the Rockies.
Josh Hamilton will miss eight weeks after suffering an injury on a strange play at home plate Tuesday. Who will replace him?
The Rangers have been dominant this season but they face an old foe Wednesday in the form of Felix Hernandez.
The Yankees look to solidify their starting rotation as they eye an AL East Crown.
Seattle ace Felix Hernandez takes the hill against the Angels on Saturday.
In a potential playoff preview between the Padres and Phillies, Adrian Gonzalez looks to extend his success against Philly's Joe Blanton.
After getting torched by Toronto hitters on Friday, Boston turns to Daisuke Matsuzaka, who has stymied the Blue Jays in previous meetings.
Need saves? The Dodgers have turned over the ninth-inning role - at least temporarily - to Hong-Chih Kuo.
Stephen Strasburg returns to the mound Tuesday, just one of several aces on the hill, including Ubaldo Jimenez, Felix Hernandez and Tim Lincecum.
Though this may be the Year of the Pitcher, Saturday is shaping up to be a hitter's paradise.
He only has 17 career at-bats against Jair Jurrjens, but Hanley Ramirez has torched the Braves pitcher for three home runs.
Alex Gordon is finally getting another chance with the Royals to live up to his potential.
A slew of batters (including the red-hot Lance Berkman) have good matchups in what promises to be a hitter-friendly Saturday.
Despite the thin air, the Giants-Rockies game on Saturday night is shaping up to be a low-scoring duel between Barry Zito and Ubaldo Jimenez.
Jonathan Papelbon has blown two consecutive saves. Is he in danger of losing his job as the closer?
Interleague play brings a lot of new matchups, but not for Albert Pujols and the Cardinals, who have plenty of history with Oakland starter Ben Sheets.
Carlos Silva has been on an unbelievable run this season and looks poised to continue his dominance against the crosstown White Sox.