Chelsea are the biggest favorites on Tuesday's three-game slate, which means plenty of fantasy players will be considering Alvaro Morata if he starts.
Sunday includes huge derbies in Liverpool and Manchester, and the bookmakers are expecting Mohamed Salah to make an impact.
Juventus v. Inter Milan is the big match on Saturday's five-game European interleague slate, but Monaco's Radamel Falcao has the best anytime goal scorer odds by a wide margin.
Harry Kane's fantasy floor is a bit higher than he gets credit for, but does that mean fantasy players have to pay up for the Spurs striker Saturday?
Harry Kane figures to be highly owned on Saturday's six-game Premier League slate, but fading him may just be too risky.
Tottenham are the dominant favorites on Saturday's six-game slate, and fantasy players will find it hard to pass on Kieran Trippier.
With Tottenham expected to dominate possession Saturday against Stoke City at Wembley Stadium, Ben Davies could have a very strong fantasy outing.
Andrew Laird and Jordan Cooper review this week's Champions League action and then dive into Saturday's six-game daily fantasy Premier League slate, which has affectionately been described as the worst of the season.
Tottenham are expected to rotate heavily for Wednesday's Champions League match against APOEL, but it could be time for Serge Aurier's coming out party.
Tottenham are the only big favorites on Saturday's six-game daily fantasy Premier League slate, which means Harry Kane and Christian Eriksen are likely to draw plenty of attention.
Liverpool need a result to ensure they move onto the next round of the Champions League, and Mohamed Salah is expected to play a big role.
A win Wednesday against Spartak Moscow will clinch the top spot in Group E for Liverpool, and they will be looking for Mohamed Salah to continue his excellent run.
Manchester United need a point against CSKA Moscow to lock up the top spot in their group, and Marcus Rashford could have an important role on set pieces.
Napoli need a win and help elsewhere to qualify for the knockout rounds of the Champions League, and they'll look for Lorenzo Insigne to make a big impact.
Roma are the biggest favorites with the highest implied goal odds among Tuesday's eight Champions League matches, and they'll rely on Edin Dzeko to lead them to the round of 16.
Paulo Dybala has yet to find the scoresheet during Champions League play, but Schuyler Redpath is expecting a breakout performance Tuesday at Olympiacos.
Andrew Laird and Jordan Cooper review their DraftKings cash lineups from this past Saturday's Premier League slate before jumping in to preview Tuesday's eight Champions League matches.
Roma will book their place in the knockout rounds with a win against Qarabag on Tuesday, and they'll rely on Edin Dzeko to put them ahead.