Carson Palmer and the Cardinals have the easiest matchup among the heavy favorites, though the game is on the road.
Davis Mattek gives thanks to three receivers, including Houston's DeAndre Hopkins, who have made a big impact this fantasy season.
The staff likes Ben Roethlisberger and the Steelers getting four points on the road against the Seahawks.
Luke Hoover breaks down the Week 12 matchups as Alfred Blue looks to have another big game against a terrible Saints defense.
Chris especially likes J.J. Watt and the Texans as three-point home favorites against the Saints.
Erik Siegrist previews the Monday Night as Johnny Manziel is still the story in Cleveland with the a banged-up Baltimore squad coming to town.
Chris Bennett will go with Eli Manning at quarterback this week in GPPs as his low price, and low ownership, make him a great value.
Two of the best defenses are hosting two of the best offenses this week - who will win out in the Steelers vs. Seahawks matchup (besides the refs)? Check out those and our other Week 12 rankings.
Andrew Martinez looks at defenses available on your waiver wire, including how the Buccaneers will fair against T.Y. Hilton and the Colts
Twelve of the league's starting quarterbacks have already missed games due to injuries, and there's a third of the season still to play.
Josh Bartilotta's Thanksgiving Day picks include Jonathan Stewart against an RB-friendly Dallas defense.
Mario Puig looks at Eddie Lacy's return to relevance, along with some rising rookies.
Jeff Stotts examines Marshawn Lynch's injury and the possibility of sports hernia surgery
Kevin Payne offers up free agents for Week 12, and at the top of the list is Seattle's Thomas Rawls, if he's still available in your league.
In his seventh annual set of Thanksgiving Day rankings, Derek VanRiper goes full homer and puts Aaron Rodgers atop the list of quarterbacks.
Andrew Fiorentino discusses the aftermath of another week with big backfield shakeups, including the return to prominence of the disappointing Eddie Lacy
Mark Stopa gives fantasy owners to cut Philip Rivers in shallow leagues as the Chargers quarterback is a one-man show without Keenan Allen.
Thomas Rawls exploded for 255 yards and two touchdowns Sunday, and he could get significantly more playing time down the stretch if Marshawn Lynch's injury is more serious than expected.